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Non-Convulsive Status Epilepticus (NCSE) in ICU

Made Wiryana , I Ketut Sinardja, I Wayan Aryabiantara, Tjokorda GdeAgung Senapathi, I Made Gede Widnyana, I Gusti Agung Gede Utara Hartawan, Pontisomaya Parami, Christopher Ryalino, Adinda Putra Pradhana

Made Wiryana
Department of Anesthesiology, Pain Management and Intensive Care, Udayana University, Sanglah General Hospital, Denpasar-Bali, Indonesia. Email: anesthesiology@unud.ac.id

I Ketut Sinardja
Department of Anesthesiology, Pain Management and Intensive Care, Udayana University, Sanglah General Hospital, Denpasar-Bali, Indonesia

I Wayan Aryabiantara
Department of Anesthesiology, Pain Management and Intensive Care, Udayana University, Sanglah General Hospital, Denpasar-Bali, Indonesia

Tjokorda GdeAgung Senapathi
Department of Anesthesiology, Pain Management and Intensive Care, Udayana University, Sanglah General Hospital, Denpasar-Bali, Indonesia

I Made Gede Widnyana
Department of Anesthesiology, Pain Management and Intensive Care, Udayana University, Sanglah General Hospital, Denpasar-Bali, Indonesia

I Gusti Agung Gede Utara Hartawan
Department of Anesthesiology, Pain Management and Intensive Care, Udayana University, Sanglah General Hospital, Denpasar-Bali, Indonesia

Pontisomaya Parami
Department of Anesthesiology, Pain Management and Intensive Care, Udayana University, Sanglah General Hospital, Denpasar-Bali, Indonesia

Christopher Ryalino
Department of Anesthesiology, Pain Management and Intensive Care, Udayana University, Sanglah General Hospital, Denpasar-Bali, Indonesia

Adinda Putra Pradhana
Department of Anesthesiology, Pain Management and Intensive Care, Udayana University, Sanglah General Hospital, Denpasar-Bali, Indonesia
Online First: February 20, 2017 | Cite this Article
Wiryana, M., Sinardja, I., Aryabiantara, I., GdeAgung Senapathi, T., Gede Widnyana, I., Utara Hartawan, I., Parami, P., Ryalino, C., Putra Pradhana, A. 2017. Non-Convulsive Status Epilepticus (NCSE) in ICU. Bali Journal of Anesthesiology 1(1): 20-24. DOI:10.15562/bjoa.v1i1.5


Epilepsy is a neurological disorder characterized by recurrent epileptic seizures. Non-convulsive status epilepticus (NCSE) is defined as a persistent change in mental status as opposed to the previous conditions, lasted at least 30 minutes long,  associated with continuous spike wave epileptiform EEG changes. Clinical manifestation of NCSE can present as confusion, personality changes, psychosis, and coma. Indeed NCSE prognosis is dependent on the underlying etiology of persistent EEG changes of. Preferred medication is focus on improving its fundamental pathological changes, such as metabolic disorders, infection, drugs toxicity, and immediate pharmacological treatment. Intravenous benzodiazepine is recommended asthe first drug of choice for NCSE and early recognition of treatment response can help to establish the diagnosis.  This patient has a good outcome which was influenced with short ictal period from the first episode upon arrival on reffered hospital, good initial response and management on emergency department, a conduct and thorough ICU monitoring, as well as the effective treatment response.

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